association between polymorphism of TCF7L2 gene rs12255372 G/T and type 2 diabetes mellitus in Iraqi women suffering from menopause

Type 2 diabetes mellitus (T2DM) became the most prevalent health problem. Almost half of world's people are ignorant that have diabetes. Menopause occurs as an important alteration in women through which take place change sex hormones, distribution fat،s body, and metabolism, altogether participate metabolism disease such type mellitus. Several studies appeared association between TCF7L2 gene different diseases like (T2DM). This study aimed to detect relation genetic variation polymorphism for (rs12255372 G/T) Iraqi menopausal with T2DM. The outcomes indicated increased levels biochemical characteristics including HbA1C, Cholesterol, Triglyceride, Prolactin, Progesterone, Estrogen decreased level HDL significant differences (P<0.05). While there was no SNP patients T2DM when compared control (P>0.05). Although a genotypes this SNP. In conclusion (rs12255372G/T) is not represented risk factor